DEVTAMIN 12 isindicated for:
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DOSAGE AND ADMINISTRATION:
Adults and Children:
Addisonian pernicious anaemia and other macrocyticanaemias without neurological involvement:
Initially: 250 to 1000mcg intramuscularly on alternate daysfor one to two weeks, then 250mcg weekly until the blood count is normal.
Maintenance dose: 1000 mcg/month.
Addisonian pernicious anaemia and other macrocytic anaemiaswith neurological complications:
Initially: 1000mcgintramuscularly on alternate days as long as improvement is occurring.
Maintenance dose: 1000 mcg monthly.
Prophylaxis of macrocytic anaemia associated withvitamin B12 deficiency resulting from gastrectomy, some malabsorption syndromesand strict vegetarianism:
250mcg -1000 mcg monthly.
Schilling Test:
An intramuscular injection of 1000mcg cyanocobalamin is an essentialpart of this test.
SIDE EFFECT:
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···Reactivethrombocytosis can occur during the first weeks of use in megaloblasticanaemia.