Methylcobalamine Injection

About Methylcobalamine Injection

DEVTAMIN 12 isindicated for:

DOSAGE AND ADMINISTRATION:

Adults and Children:

Addisonian pernicious anaemia and other macrocyticanaemias without neurological involvement:

Initially: 250 to 1000mcg intramuscularly on alternate daysfor one to two weeks, then 250mcg weekly until the blood count is normal.

Maintenance dose: 1000 mcg/month.

Addisonian pernicious anaemia and other macrocytic anaemiaswith neurological complications:

Initially: 1000mcgintramuscularly on alternate days as long as improvement is occurring.

Maintenance dose: 1000 mcg monthly.

Prophylaxis of macrocytic anaemia associated withvitamin B12 deficiency resulting from gastrectomy, some malabsorption syndromesand strict vegetarianism:

250mcg -1000 mcg monthly.

Schilling Test:

An intramuscular injection of 1000mcg cyanocobalamin is an essentialpart of this test.

SIDE EFFECT:

Reactivethrombocytosis can occur during the first weeks of use in megaloblasticanaemia.