Each film coated tablet contains:
Chloroquine Phosphate BP
Equivalent to Chloroquine ..............150 mg
Excipients ........................................... q.s.
Colour: Titanium Dioxide
QINODEV is indicated for suppressive treatment and for acute attacks of malaria due to P. vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. The drug is also indicated for the treatment of extraintestinal amebiasis.
Chloroquine Phosphate Tablets do not prevent relapses in patients with vivax or malariae malaria because it is not effective against exoerythrocytic forms of the parasite, nor will it prevent vivax or malariae infection when administered as a prophylactic agent. It is highly effective as a suppressive agent in patients with vivax or malariae malaria, in terminating acute attacks, and significantly lengthening the interval between treatment and relapse. In patients with falciparum malaria it abolishes the acute attack and effects complete cure of the infection, unless due to a resistant strain of P. falciparum.
DOSAGE AND ADMINISTRATION:
Malaria Suppression - Adult Dose: 500 mg (= 300 mg base) on exactly the same day of each week.
Pediatric Dose: The weekly suppressive dosage is 5 mg calculated as base, per kg of body weight, but should not exceed the adult dose regardless of weight.
For Treatment of Acute Attack Adults:
An initial dose of 1 g followed by an additional 500 mg after six to eight hours and a single dose of 500 mg on each of two consecutive days. This represents a total dose of 2.5 g chloroquine phosphate of 1.5 g base in three days.
The dosage for adults of low body weight and for infants and children should be determined as follows:
First dose: 10 mg base per kg
Second dose: 5 mg base per kg
Third dose: 5 mg base per kg.
Fourth dose: 5 mg base per kg.
For radical cure of vivax and malariae malaria concomitant therapy with an 8-aminoquinoline compound is necessary.
Adults: 1 g daily for two days, followed by 500 mg daily for at least two to three weeks. Treatment is usually combined with an effective intestinal amebicide.
Store at Room Temperature away from heat and light.
Keep out of reach of children.
100 x 10 Tablets in Printed Carton with pack insert.